Adaptive Control of Insulin Delivery for Diabetic Patients
The complications of diabetes are thought to arise from poor control
of blood glucose concentration because of inadequate secretion of
insulin by the pancreas. This has motivated the undertaking of novel
therapeutic approaches to improve insulin delivery.
Present insulin administration requires insulin injections which, even
in their simplest form of the Novo-pen system, are cumbersome and
undesirable by the patient. Controlled drug delivery technologies can
be used to our advantage to provide delivery of insulin over a period
of time at specified rates. Indeed, as we show below, controlled drug
delivery(CDD) systems can be developed to release insulin only when
the glucose level in the blood is abnormally high.
The goal of this project is to design adaptive controllers such as the
adaptive lambda-tracker and demonstrate how much improvement these
controller yield compared to standard controllers.