A Glossary for Systems Biology
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STATIC (BEHAVIOR)
dynamic (behavior), model
Static behavior of a system is defined in systems theory
as a system's behavior at an equilibrium point.
Often measurements can only be taken while a system is in a stable
state (i.e. at equilibrium), because changes within the system are
too fast to be measured and would invalidate the measured data. Models
of such systems - when based exclusively on the empirical data from
measurements - are often deliberately constrained to the system's
behavior at that stationary point and leave out the more dynamic
aspects of a systems behavior. A typical example is that of a bioreactor,
which is clearly designed to operate around an equilibrium point that
ensures optimal conditions for the microorganisms in the reactor.
The model needed to run the reactor during production can be constrained
to the equilibrium of optimal growth conditions and leave out other
aspects, like start-up or shutdown phases.
Behavior within a small area around such an equilibrium point is called
local dynamic behavior and can be represented
by a linearization (dynamic) of the original system.
- model of a bioreactor during production
- system in stationary state
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